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SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.3
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%
Saturated Fat
0 g
0%
Trans Fat
0 g
†
Vitamin D3 (cholecalciferol)
25 mcg (1000 IU)
125%
Total Omega-3s♦
1280 mg
†
EPA (Eicosapentaenoic Acid)
650 mg
†
DHA (Docosahexaenoic Acid)
450 mg
†
Top Medical Research Studies
9.5
Eicosapentaenoic acid benefits CFS
Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes.
High relevance to CFS treatment
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
Read More
9
Eicosapentaenoic acid shows promise
The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome.
Highly relevant to the study focus
We examined the link between chronic fatigue syndrome (CFS) and essential fatty acids, focusing specifically on eicosapentaenoic acid (EPA). This investigation arose from various studies highlighting the potential role essential fatty acids play in alleviating symptoms associated with CFS.
Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.
These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.
These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
Read More
2
Vitamin D3 ineffective for CFS
Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial.
Directly tests treatment effectiveness
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.
Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.
In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.
In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More
Most Useful Reviews
8.8
Mood lifting effects
A Converted Skeptic: After researching, I decided to try Omega 3, and Nordic Naturals came highly recommended. The product has surpassed my expectations. I've noticed a boost in my mood and my sore knees feel less painful, though I still rely on prescription anti-inflammatories while awaiting knee surgery. I also recommended it to a friend with chronic fatigue syndrome, and her mood has improved significantly since starting the supplements.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.3
9.5
Eicosapentaenoic acid benefits CFS
Eicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changes.
High relevance to CFS treatment
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
Read More
9
Eicosapentaenoic acid shows promise
The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome.
Highly relevant to the study focus
We examined the link between chronic fatigue syndrome (CFS) and essential fatty acids, focusing specifically on eicosapentaenoic acid (EPA). This investigation arose from various studies highlighting the potential role essential fatty acids play in alleviating symptoms associated with CFS.
Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.
These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
Our approach involved administering a high-EPA supplementation to a group of individuals diagnosed with chronic fatigue syndrome. After following these patients for eight to twelve weeks, we observed that all participants experienced notable improvements in their symptoms.
These positive changes align with recent findings that discuss both cerebral and clinical benefits tied to increased EPA intake. Given these encouraging results, eicosapentaenoic acid may ultimately provide hope for many suffering from chronic fatigue syndrome.
Read More
9
Effective treatment for fatigue syndrome
Effect of high doses of essential fatty acids on the postviral fatigue syndrome.
Assessing EPA's role in fatigue
We conducted a thorough investigation into the effects of essential fatty acids, including eicosapentaenoic acid (EPA), on individuals suffering from postviral fatigue syndrome. In a well-structured trial, 63 adults with this condition participated in a double-blind, placebo-controlled study. They had been living with severe fatigue and other troubling symptoms for one to three years following a viral infection.
Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.
Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.
Patients received either an active treatment containing EPA and other essential fatty acids or a placebo for three months. Their overall health, fatigue levels, and other symptoms were assessed at the beginning, after one month, and at the end of the study. Strikingly, we observed that 74% of those taking the essential fatty acids reported improvements after one month, rising to 85% after three months. In contrast, only 23% and 17% of the placebo group noted any benefit at those respective time points.
Notably, the fatty acid levels in the participants' red blood cells, which were abnormal at the beginning of the trial, showed significant improvement with the active treatment. Importantly, we found no adverse side effects from the treatment, leading us to conclude that essential fatty acids can be a safe and effective option for people dealing with postviral fatigue syndrome.
Read More
9
Essential fatty acids aid fatigue syndrome
Effect of high doses of essential fatty acids on the postviral fatigue syndrome.
Study shows DHA's potential benefit
We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.
In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.
Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.
Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.
Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.
Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
Read More
8
Beta-glucan shows cognitive improvements
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Vitamin D3 effects unclear
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.
Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Mood lifting effects
A Converted Skeptic: After researching, I decided to try Omega 3, and Nordic Naturals came highly recommended. The product has surpassed my expectations. I've noticed a boost in my mood and my sore knees feel less painful, though I still rely on prescription anti-inflammatories while awaiting knee surgery. I also recommended it to a friend with chronic fatigue syndrome, and her mood has improved significantly since starting the supplements.
Read More
